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As metal ions can enter into the cell via endocytosis complexed to chelating proteins such as metallothioneins, it is easy to conceive that decreasing endocytic rates can be considered as a protective mechanism to avoid metal-induced toxicity

Niacinamide (vitamin B3): It can promote skin metabolism, regulate the oil and water balance of the skin, prevent skin aging, and reduce wrinkles and spots

The main dietary intake-related antioxidants include tea, coffee, red wine, Vitamin C (ascorbate), Vitamin E (alpha-tocopherol and gamma-tocopherol), carotene, Vitamin A (retinol), Zinc, and Selenium

valos A, Haza AI, Mateo D, Morales P

Localized irritation, redness, or tingling at the injection site

Gardner, H