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doi: 10.3389/fimmu.2021.755862 56 SimpsonDSPangJWeirAKongIYFritschMRashidiMet al

Acknowledgements The authors would like to extend their appreciation to the Deanship of Scientific Research, King Saud University for funding through Vice Deanship of Scientific Research Chairs

When NOT to

Once the gut barrier is damaged, so too is the gut-brain barrier

Leichert, A.J

Specifically, it displays certain immunomodulatory and anti-inflammatory properties, including the promotion of Foxp3 + regulatory T cells, strengthening the structural integrity of the gut mucosal defense system, and suppression of pro-inflammatory Th2 and Th17 pathways [45]