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But dose reduction is a legitimate strategy in several situations

RP-HPLC separates the target complex from related species using a solvent gradient and resolves it as a dominant chromatographic peak under UV detection, allowing chromatographic purity to be assessed

10.1002/bies.10077 35 CzaplaJ.MatuszczakS.KulikK.WiniewskaE.PilnyE.Jarosz-BiejM.et al (2019)

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Ethics declarations Ethics approval and consent to participate This study did not involve human participants or animals