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Here are some signs that you should talk to a doctor sooner: Very bad pain that doesnt get better with pain medicine A lot of swelling, redness, or warmth around where you got the shot Fever, chills, or feeling very sick Trouble moving your arm A rash or itching all over your body Which Vaccines Cause the Most Pain

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They can lead to signs of premature aging and chronic diseases or conditions

doi: 10.1016/j.arcmed.2005.05.014 21 CamachoA.MontielT.MassieuL

Statistical analysis Statistical analysis was performed using Prism software (GraphPad Software), and results are presented as the mean s.e.m