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L., Roberts, M

Intracellular metabolites (GSH, glucose, glucose-6P, pyruvate, succinate) were measured by liquid chromatography (Vanquish HPLC Thermo Scientific) coupled to high resolution mass spectrometry (QExactive HF Thermo Scientific)

Pathophysiology of Dercum Disease The pathophysiology of Dercum disease needs to be determined by type, something that very few papers have done so accurately

200 Enzyme-catalyzed reactions that generate ROS include those involving NADPH oxidase, xanthine oxidase, uncoupled endothelial nitric oxide synthase (eNOS), arachidonic acid and metabolic enzymes such as the cytochrome P450 enzymes, lipoxygenase and cyclooxygenase

As one of the risk factors, obesity has a role in OA, including increased joint loads, altered metabolism, and low-grade inflammation [33]

Without catalase, excess H 2 O 2 generated by SOD can react with metal ions, leading to the formation of the highly destructive hydroxyl radical