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A secondary analysis of the randomized clinical trial EFFORT

The Wt+R+V mice had significantly higher levels of AGEs (10.95 0.88 SEM) in the midbrain compared to both healthy controls (3.37 0.67 SEM, p = 0.002) and Wt+R+E (5.88 1.02 SEM, p = 0.02) (Fig

Arthritis Care Res

paracasei LMG-S-26420 was grown in a Sartorius fermenter (Biostat A Plus model) for 24 h at 37 C, at pH 5.5, and controlled by 5M NaOH

Additionally, a profound decline in FBS, insulin, and HOMA-IR ( p = 0.014, 0.051, 0.024, respectively) and an increment in QUICKI ( p = 0.019) were observed in the L-carnitine + synbiotic group compared with the L-carnitine + placebo group post-intervention, which remained significant after adjustment for the baseline levels and possible confounding factors

Br J Med Med Res 12(1):18