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Recent molecular dynamics simulations reveal that UV-A irradiation (350 nm) induces trans-cis configurational changes at the CC double bonds in the heptadienone linker, generating photoisomers that serve as precursors for photodimerization via [2 + 2] cycloaddition or photooxidation (H-loss) pathways [64]

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An overview of the major challenges and corresponding solutions is illustrated in Figure 5

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Porges, J.J