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In this context "substantially free" of aggregates means that the amount of aggregates remains lower than 10%, 9%, 8%, 7%, 6%, 5%, 4%, 3%, 2% or 1 % (w/v), particularly also when being subjected to environmental stress, e.g

Felker P, Bunch R, Leung AM (2016) Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism

This finding is clinically significant for a patient population like ours in Doral, where the majority of patients present with Fitzpatrick III, IV, and V skin tones

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10.3390/antiox12040955 [DOI] [PMC free article] [PubMed] [Google Scholar] Chang D, Nalls MA, Hallgrmsdttir IB, Hunkapiller J, van der Brug M, Cai F, Kerchner GA, Ayalon G, Bingol B, Sheng M, Hinds D, Behrens TW, Singleton AB, Bhangale TR, Graham RR, 2017

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