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Description

While severe inborn errors of folate metabolismsuch as those causing homocystinuriaare rare and typically result from deletions or deleterious mutations that abolish enzyme function, their dramatic clinical consequences have underscored the critical importance of this metabolic pathway [1-3]

Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2

After rinsing with 1% HNO 3 , the final volume was adjusted to 10 mL with distilled water which was thereafter filtered and stored in 30 mL glass vial for further analysis on ICP-MS [38]