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Electron microscopy study Specimens were fixed in 3.2% glutaraldehyde and post-fixed in 1% osmium tetroxide, at 4C and for 60 min, washed with PBS (0.1 M

151 Furthermore, in both murine and human cells, ATM kinase has been confirmed to be responsible for recruiting telomerase, an enzyme in charge of length maintenance of telomeres, which indicates that inhibiting ATM activity leads to progressive telomere shortening, a classic aging hallmark

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Finally, molecular docking study confirmed the conservance of substrates (GSH and CDNB) binding sites to GST during the detoxification reaction

21.Mo, N., & Ec, L