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doi:10.3389/fendo.2021.684096 Ruigmez A, Garca Rodrguez LA, Johansson S, Wallander MA

doi: 10.1016/j.bbih.2021.100266 3 ChenM

Excessive glucocorticoid activity due to cortisol is known as hypercortisolism, hence this form of Cushings syndrome is titled pituitary-dependent hypercortisolism (PDH)

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Another computational study examined 257 compounds with FIASM activity and found that, in particular, cepharanthine and zafirlukast (a leukotriene antagonist) were the top hits, having very strong binding affinities (G 9.5 kcal/mol) and favorable drug-like properties (7)