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Description

J Pediatr 165:528533

Science 337 , 10621065 (2012)

However, MEKK2 exhibits undetectable kinase activity, and its kinase mutant still mediates autoimmunity 17,18

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The link between UPS impairment and PD pathogenesis is increasingly clear because in addition to -synuclein, Lewy bodies also contain ubiquitin, parkin and other proteasomal proteins [355-357] (Fig