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28 Co-occurring conditions like anxiety, depression, stress, and sleep disorders can be contributors, while disturbances that are difficult to diagnose, such as dysregulated stress reactivity, neurotransmitter imbalance, inflammation, mitochondrial dysfunction, free radical damage, hormonal imbalance, and metabolic disturbance, as well as crosstalk between these factors, may also play a role

Future studies should also include younger and premenopausal women to clarify vitamin K's role in glucose metabolism, insulin sensitivity, and type 2 diabetes prevention

Meanwhile, overall aging indicators were significantly improved: locomotor activity and endurance were enhanced, hair gloss increased, levels of aging-related inflammatory factors (such as TNF-, IL-6) decreased, and the average lifespan of mice was prolonged

It is thought to interact with beta-3 adrenergic receptors, which are involved in regulating fat metabolism

In terms of population acceptability, Wong et al