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Chasing molecular glue degraders: screening approaches

Torres et al., 2017) (Williamson et al., 2019)

ACD, iron overload disease d

doi: 10.1038/s41467-018-07295-7 150 MaQ.LuH.XuZ.ZhouY.CiW

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An equivalent amount of protein from each animal was mixed with 4 sample buffer with or without 2-mercaptoethanol, then separated by SDSpolyacrylamide gel electrophoresis, and transferred electrophoretically to a PVDF membrane (Merck Millipore)