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Conditions Commonly Caused by B12 Deficiencies B12 deficiencies are common and can cause a wide range of symptoms and health issues, including: Depression Fatigue, including chronic fatigue Poor concentration and memory Insomnia and other sleep disorders Headaches Heart disease Anemia Digestive disorders, including irritable bowel syndrome (IBS) Peripheral neuropathy Nearly anyone can suffer from a B12 deficiency

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The development of goniometers and photometers in the 1950s and the invention of the laser in the 1960s, which provided a monochromatic, well-collimated light source, significantly improved the accuracy and ease of light scattering measurements