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Excretion and clearance 7

Investigator-assessed improvement Finding: The blinded investigator assessed the active treatment group as showing Scale 1 improvement (2650% improvement) at the final visit, while the placebo group showed Scale 0 improvement (025%)

Two features of the preclinical dose-response data are particularly relevant for researchers designing studies

Rather than trying to force a peptide through the gastrointestinal barrier using formulation technology, several research groups asked whether a small, non-peptide molecule could be designed to activate the GLP-1 receptor directly

Taking penta deca peptide arginate orally means retaining approximately 95% of the dose through gastric transit