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Regardless, these results point towards a meaningful role of p21 in regulating cell fate that is only partly dependent on p53

This decline in NAD+ levels makes it harder for us to fix cellular damage and can "turn off" genes that speed up degenerative aging

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doi: 10.3389/fimmu.2021.677550 81 Prez-PrezAVilario-GarcaTFernndez-RiejosPMartn-GonzlezJSegura-EgeaJJSnchez-MargaletV