Eligible U.S
Most people can, but there are a few exceptions (for example, people with certain rare medical conditions)

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The items below are route-related and general-caution considerations, not a validated adverse-event list
The prevalence of B12 deficiency in those older than 60 years is between 10% and nearly 20%.7,8 Because multiple causes can coexist in elderly patients, including poor absorption, protracted metformin use, and reduced dietary intake, these patients have the greatest risk for B12 deficiency and should be carefully monitored for signs of deficiency
Patel, S., Yang, W., Kozusko, K., Saudek, V