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To this regard, a recent pharmacogenomic GWAS study carried out on 455 HS patients, investigating genetic variants associated with response to Adalimumab, has identified a SNP in the gene of the anti-apoptotic factor BCL2, thus suggesting a potential role of apoptosis regulation in the pathophysiology of Adalimumab response

Moreover, knowing that the combinations of arsenic trioxide with targeted drugs such as mTOR (Guilbert et al., 2013

Administered as an injectable or oral troche

E.Ceballos-DiazC.et al

Receptors and Neurotransmitters of the CNS transporter gene Gene A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms

Yanatori, I., Richardson, D