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Ortiz, G.G., M.A

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The BBB of mice was found to be largely intact, as confirmed by various assays for leakage of components of the periphery into the CNS, including horseradish peroxidase [39, 40], immunohistochemistry [40], and radioactive tracers [41], which is why it was long believed that the cuprizone-induced demyelination occurs without peripheral involvement

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It supports instructional use within research, teaching, and simulation facilities where a preserved water-based medium is required

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