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These mediators can contribute to the inflammatory cascade

For licensed GLP-1 receptor agonist medicines used for weight management (Wegovy and Saxenda), the side effect profile is well characterised in their UK Summaries of Product Characteristics (SmPCs), available via the electronic Medicines Compendium (emc)

Pregnant or Nursing Individuals : Limited data on the safety of peptides during pregnancy and lactation suggest caution

Taken together, these results might reflect increased consumption of GSH in the PCC during aging

Issue: Side effects from systemic peptide injection Common side effects: Injection site reactions (redness, swelling, tenderness), nausea (especially with higher doses), headaches, fatigue, blood pressure changes, allergic reactions (rare but serious)