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A loss of bioenergy and biosynthetic homeostasis was reported, which could be explained by significantly reduced concentrations of intermediate metabolites such as pyruvate, lactic acid, and pyruvate kinase (a key enzyme in glycolysis) in placenta (16)

38 The release of lysosomal enzymes into the cytosol is dependent on the specific lysosomal enzyme cathepsin B

SunQChengZChengDChenJJiSWenJet alDe novo development of circulating anti-endothelial cell antibodies rather than pre-existing antibodies is associated with post-transplant allograft rejection