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When the body is dehydrated, blood volume decreases, which can cause a drop in blood pressure and result in feelings of dizziness or even fainting

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Activation of inflammasomes UVB can also disrupt protein synthesis and induce DNA damage within cells, causing ribosomes to collide with other molecules in the cytoplasm and producing ribotoxic stress response (RSR), which initiates an activation of the NLRP1 inflammasomes facilitating the maturation and subsequent excretion of key pro-inflammatory cytokines (such as IL-1, IL-18) that promote the development of skin cancer by enhancing inflammation and immune suppression [131, 132]

(PubMed) Ziegler D, Hanefeld M, Ruhnau KJ, et al

JCI Insight 8 , e161812 (2023)

References 1.Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y