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In addition, the co-occurrence and potential interdependency of catabolic and anabolic transformations of natural and synthetic chlorine compounds are discussed for selected microorganisms and particular ecosystems

Sci Transl Med (2011) 3(104):104ra102

J Gerontol A Biol Sci Med Sci 58 : 648652 Ketelslegers JM et al

The molecular pathogenesis of DOX-induced chemobrain is attributed to excessive generation of ROS or the decline in the antioxidant defense, resulting in oxidative stress that has been linked to neuroinflammation and neurotransmitter imbalance [39, 40]