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Malaguarnera M, Gargante MP, Cristaldi E, et al

(2022) 10:e005020

1990 doi: 10.1073/pnas.87.11.4063

The excess load of copper can enhance cell toxicity and oxidative stress and damage cell growth

Moreover, treatment of CC mice with NA rescued NAD + levels in skeletal muscle, improved muscle function, and increased Oxphos complexes expression, yet NA treatment had no effect on mitochondrial respiration 248