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The more glutathione in circulation, the better the body is at combating oxidative stress and preventing the associated diseases

We observed neither an NMD-dependent increase in general HIF-1 activity nor a hif-1- dependent increase in NMD activity, indicating that neither NMD nor HIF-1 acts strictly upstream of the other

Consistently, SOD1 G93A transgenic mice exhibited ferroptotic features and neurotoxic glial activation resembling those observed in ALS patient spinal cords and in vitro models

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