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A critical underlying mechanism involves oxidative stress (OS), an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, which disrupts endothelial function, reduces nitric oxide (NO) bioavailability, and contributes to vascular dysfunction

EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells

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Reflecting the clinical importance of tendon injuries and the challenge of achieving complete functional repair in tissues with limited intrinsic regenerative capacity

[298] In that final rule, we explained that such circumstances are limited to when a manufacturer's data for a multiple source drug product with sales during a quarter is missing, and efforts to obtain manufacturer reported ASP data before Medicare ASP payment limits publication deadlines have not been successful