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Research has shown that polyphenols offer several biological and therapeutic benefits, including antioxidant, anti-AS, and antiinflammatory properties, useful in treating human diseases (323)

Notably, the role of mTOR in glutamine use has a number of clinical implications, as various studies have investigated the targeting of this signaling pathway with mTOR inhibitors as a novel therapeutic approach

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Song et al showed that decreasing periplasmic GSH by deleting the GSH exporter CydD triggers the CpxR/SoxS two-component systems, upregulating the AcrAB-TolC pump and lowering intracellular drug accumulation

While the FDA stamped Rifabutin for tuberculosis, the functional medicine world is now harnessing its off-label uses for chronic Lyme, especially those nasty intracellular forms, and for Bartonella co-infection treatment

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