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Piavchenko et al., 2025a

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It also appears to modulate key growth factors, like Vascular Endothelial Growth Factor (VEGF), which act as signals to kickstart the healing cascade

This proof-of-concept in an animal model of autoimmunity provided the rationale to design human clinical trials in which Larazotide acetate was initially tested in an inpatient, double-blind, randomized placebo controlled trial to determine its safety, tolerability, and preliminary efficacy (14)

Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on December 2nd, 2025

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