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doi: 10.1021/bc900393r

Vitamin K2 protects PC12 cells against A (1-42) and H2O2-induced apoptosis via p38 MAP kinase pathway

D-glucarate is also found naturally in grapefruit, apples, oranges and cruciferous vegetables

This inhibition results in MFN2 proteasomal degradation and decreased expression, which in turn promotes the proliferation of pulmonary artery smooth muscle cells and inhibits their apoptosis (Dasgupta et al., 2021