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Yin J, Wu M, Duan J, Liu G, Cui Z, Zheng J, et al

The Nrf2/GCH1/BH4 axis ameliorates radiation-induced skin injury by modulating the ROS cascade

Importantly, the application of ferrostatin-1 successfully mitigated the ferroptosis and EMT-related dysfunctions, indicating promising pathways for therapeutic intervention ( Tumor protein p53 (TP53) , Enhancer of Zeste Homolog 2 (EZH2 ), Tissue inhibitor matrix metalloproteinase 1 (TIMP1) , Solute carrier family 3 member 2 (SLC3A2), and Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) (Zeng et al., 2025)

gsh mutants produce lower pyoverdine levels Pyoverdine is a green fluorescent siderophore that is also involved in P

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Consequently, tumor cell subpopulations with specific metabolic affinities and potentially unique therapeutic vulnerabilities have been recently identified in glioma (Al-Dalahmah et al, 2023