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Br J Pharmacol (2019) 176(17):318092

National Library of Medicine (2022)

Dynamic macrophage phenotypes in autoimmune and inflammatory rheumatic diseases

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Supplement Facts Amount per Serving % Daily Value Calories 35 Total Carbohydrates 9 g 3% Calcium 30 mg 2% D-Ribose (Bioenergy Ribose Brand) 5,000 mg * Acetyl L-Carnitine 500 mg * Malic Acid 300 mg * N,N-Dimethylglycine HCl (DMG) 100 mg * Rhodiola rosea Extract 75 mg * yielding rosavins 2.25 mg Coenzyme Q10 30 mg * Bromelain 1,000 mg * Protease (from Aspergillus niger ) 1,000 mg * Stevia Leaf Extract 45 mg * Other ingredients : natural orange powder, citric acid, natural orange flavor, silica, tricalcium CAUTION: Jar contains desiccant to reduce moisture and clumping

Many mammalian studies have shown that only l-carnitine has beneficial effects ( Reference Liedtke, Nellis and Whitesell 16 Reference Spasov, Iezhitsa and Pisarev 18 ) , while d-carnitine can interfere with the uptake and transport of l-carnitine ( Reference Vernez 13 , Reference Paulson and Shug 19 ) , and therefore inhibit the -oxidation of FA ( Reference Spasov and Iezhitsa 20 , Reference Leichter, Ottem and Hahn 21 ) , which has a hepatotoxic effect ( Reference Arafa 22 )