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4 Discussion: bottlenecks in current technology and future of research in alpha-synucleinopathies The discovery of the strong clinical correlation between Type 2 diabetes and neurodegeneration and the molecular crosstalks involved therein has opened up new avenues of research in elucidating the molecular and physiological basis of cognitive decline, but at the same time it has also seriously complicated our understanding of complex neurodegenerative diseases such as PD and other alpha-synucleinopathies

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The role of NRF2 has been confirmed beyond initial assumptions, presenting both challenges and opportunities in cancer treatment [69]

Affinity purified protein samples were further resolved by size exclusion chromatography and assessed by SDS-PAGE and negative stain TEM before vitrification and cryo-EM imaging (Supplementary Fig

Administration of thiourea to laboratory animals has caused a reduction in weight gain and enlargement of the thyroid gland and resulting symptoms of hypothyroidism

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