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This suggests that the TLR4-NOX4 axis is a potential therapeutic target for treating heart failure (130)

This is the first study in which 4-HNE has been measured in the serum of pwMS, revealing significantly lower levels than in the control groups

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5.2 DNA methylation The transcriptional regulation of redox-related genes in the retina is influenced by the methylation of cytosine residues in DNA, a critical epigenetic mechanism that responds to environmental changes (119)