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In addition, the likelihood of developing NASH increases with the severity of obesity.11,36 There is a universal association between NASH an insulin resistance regardless of body mass index, suggesting that insulin resistance is a central factor in the pathogenesis of NASH.38 The elevated expression of TNF-a in the liver seen in NAFLD can represent a link between the development of insulin resistance and hepatic steatosis

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It should also be avoided during pregnancy and breastfeeding

Collaboration between healthcare providers, including autism specialists and HBOT clinicians, is essential in developing individualized treatment plans tailored to the unique needs of each individual with autism

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an increased rate of resistance (in ~ 30% patients) due to inconsistent pharmacokinetics, genetic variability in TKI binding sites and associated toxicities nilotinib was introduced as a second line TKI with a separate binding site