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Although upstream mediators are able to affect TGF- in pathological events, increasing evidence exhibits that TGF- signaling pathway can induce fibrosis and tracheal stenosis by stimulation of down-stream fibrotic mediators PI3K/Akt (Xiao et al., 2020)

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None of the studies particularly caught our eyes this week, with one of the studies (paper two (2) ) being on the use of CBT in a range of chronic health conditions, with the introduction claiming that CBT is an evidence-based treatment for ME/CFS (which is against the new NICE guidelines advice)

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[35] reported the results of acute and chronic Cd toxicity tests on honey bee larvae through dosing of an artificial diet (53% W/W commercial freshly frozen royal jelly, 6% glucose, 6% fructose, 1% yeast extract, and 34% ultrapure water), showing substantial variation as compared to foragers

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