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In addition to TLR-7 agonists and TLR-7/8 agonists, M2pep-rHF-CpG nanoparticles formed by the TLR9 agonist CpG oligonucleotide (CpG ODN) are enclosed in human ferritin heavy chain (rHF) nanocage engineered by mouse M2 macrophages, these nanoparticles can be targeted to deliver to M2 TAMs and polarize M2 TAMs into M1 TAMs thereby inhibiting tumor growth (44)

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There is no data available to determine whether there is cross-allergy with Chinese herbs that have been used as blue/green dye, such as Ban Lan Gen (Radix isatidis), Da Qing Ye (Folium isatidis) and Qing Dai (Indigo naturalis)

The crude product was purified by flash column chromatography (petroleum ether-EtOAc, 99:1) to give the title compound 814 (2.50 g, 98%) as a colourless liquid

Free radicals are a type of unstable atom that can cause cellular damage and illness