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it is closely related to mitochondrial quality control in various cells and is often accompanied by apoptosis, pyroptosis, and ferroptosis of macrophages as well as endothelial cells [221]

In glutamine-addicted squamous cell carcinoma (SCC) cancer cells, V-9302 treatment inhibits the YAP1/TEAD signaling pathway to weaken the SCC cancer phenotype (Mickle, 2022)

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However, the precise function in the cell types affected by the disease remains unknown

Rivera-Delgado D, Kantarjian H, Borthakur G, Konopleva M, Kanagal R, Pemmaraju N, Daver N, Dinardo C, Takahashi K, Jabbour E, Montalban-Bravo G, Yilmaz M, Pierce S, Andreeff M , Bhalla K, Garcia-Manero G, Ravandi F, Kadia TM

This physiological response activates heat-induced adaptations similar to those produced by moderate-intensity exercise