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Acta 122 SchepL

Light is the predominant environmental factor that synchronizes circadian rhythms in mammals on a daily basis [3]

GSH also protects cells by supporting DNA repair, possibly by stabilizing repair enzymes such as DNA polymerase (Rooseboom and Schaaf, 2002)

The preventive role of Spirulina platensis ( Arthrospira platensis ) in immune and oxidative insults in a stress-induced rat model

As with the female side, the evidence that antioxidant supplements change outcomes is low to very low certainty rather than settled: the 2022 Cochrane review of antioxidants for male subfertility rated its findings as low-to-very-low certainty evidence

Discussion These therapeutic effects position ondansetron as a promising candidate for further investigation in clinical settings for the treatment of diabetes and NAFLD and, hence, support the use of the drug repurposing approach for addressing the growing burden of metabolic diseases