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Another important cause of folate deficiency is the presence of autoantibodies against folate receptors in the patient's body, which block the transport of folate across the blood-brain barrier

Studies using MRI and 3D reconstruction techniques have demonstrated that these variations can influence the ligaments biomechanical performance and susceptibility to injury

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The animal studies used both local application at the injury site and systemic administration (intraperitoneal and intragastric), with both routes showing significant effects

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