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Conclusion In sum, perturbation of Met metabolism may promote the damage process of hepatobiliary injury triggered by viral infections/toxins and/or niche abnormalities, with dysregulated inflammatory and immune responses of the liver, and contribute to the obliteration and eventual fibrosis and atresia of the bile ducts in the initiation/progression of BA

Nuclear Fructose-1,6-Bisphosphate inhibits tumor growth and sensitizes chemotherapy by targeting HMGB1

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Differences between Arabidopsis and wheat in response to moderate excess light regimes at the subcellular level may arise from the different light intensity optima ( Arabidopsis : 100150 mol m 2 s 1 , wheat: 250 mol m 2 s 1 ) of both plants, and Arabidopsis may require thus faster signaling and adaptation

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Differential effects of alcohol drinking pattern on liver enzymes in men and women