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Presynaptic dopamine depletion determines the timing of levodopa-induced dyskinesia onset in Parkinsons disease

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When sulfonylureas were used in combination with metformin, the HR decreased to 0.4, suggesting that sulfonylureas, in combination with metformin, had a protective effect on PD

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PPARG-related genes and intramyocardial triacylglycerols were shown to be greater in people with lower cardiac expression levels of SIRT1 (Majeed et al., 2021)