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INSULIN-LIKE GROWTH FACTOR-I Physiology of IGF-I GH acts both directly through its own receptor and indirectly through the induced production of IGF-I

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doi: 10.1371/journal.pone.0189117 123 TownsendJ.BrazC

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This is because HDL is responsible for removing the bad cholesterol from the blood and taking it back to the liver to be disposed, preventing the buildup of plaque in the arteries