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By blocking NNMT activity, it increases critical cellular metabolites (SAM, NAD) that drive downstream increases in energy expenditure and metabolic health 1-4

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However, translating mouse fat metabolism data to human outcomes requires substantial caution

Helps the body switch more easily between burning sugar and burning fat for fuel

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Scientists use it as a biochemical probe to better understand NNMT's contributions to lipid metabolism, mitochondrial function, and metabolic signaling networks