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In addition, the Welch t -test revealed that carbohydrates, nucleotides, peptides, vitamins, and cofactors exhibited significant correlations across various mutation backgrounds

Polyphenols mitigate the necrosis and apoptosis in myocardial cells, decrease the infarct size of heart, and enhance cardiac function by reducing ROS or reactive nitrogen-free radical production stemming from oxidative stress (187) (Figure 4)

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By protecting these compounds from degradation and promoting controlled, targeted release, nano-delivery systems make these polyphenols more effective for use in health and disease management applications