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Lipid metabolism can modulate apoptosis and autophagy by affecting the production of ROS, activation of signaling pathways, and formation of lipid droplets or membrane structures (192)

Biomater Med

Nanocrystals and solid lipid nanoparticles (SLNs) further enhance bioavailability and biocompatibility but face limitations like aggregation risk or low drug loading capacity (16)

More injections and/or higher doses will be needed for better results

These data suggest that alternative oxidase can be crucial under nitrosative stress: The high alternative oxidase activity can maintain respiration at low cytochrome c oxidase activity and reduces the activity and hence superoxide production of cytochrome bc1 complex

54,55 Opa1 is localized in the inner mitochondrial membrane, which is responsible for the fusion of the inner membrane, and maintains the membrane structure