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Compared with patients undergoing rehabilitation alone, those receiving curcumin reported greater long-term reductions in pain severity over a six-month follow-up period

This pathway activation is a result of CIN-induced cytosolic DNA release, which activates the cGASSTING pathway and downstream NCNFB signaling

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But Kennedy, the chemical biologist, says this logic doesn't necessarily mean they will be safe when injected in higher doses and then circulated in the bloodstream, "potentially reaching other places they couldn't normally access." "Even if it may have anti-inflammatory properties as injected into your knee and we see some reduced swelling there, if it causes liver failure, it's a concern, right

6.3 Stem cell-derived EVs: redox-modulating nanotherapeutics Stem cell-derived EVs have emerged as functional nanotherapeutics capable of modulating redox balance, inflammation, and tissue repair in the context of ovarian aging (Geng et al., 2023