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In the SURPASS clinical trial program in type 2 diabetes mellitus (T2D), tirzepatide was associated with unprecedented reductions in HbA1c, clinically significant weight loss and other metabolic benefits, combined with low rates of hypoglycaemia across a wide range of patient characteristics

Mechanistically, this makes sense

Wu KK, Kuo C-C, Yet S-F, Lee C-M, Liou J-Y

As an emerging field of intense investigation, ferroptosis mechanisms and their associated pathways have garnered significant attention

Farina M, Rocha JB, Aschner M (2011) Mechanisms of methylmercury induced neurotoxicity: evidence from experimental studies

Provides botanical support for the DHT pathway