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327 One major mechanism of apoptosis resistance in CSCs is the upregulation of antiapoptotic proteins, including BCL-2, BCL-XL, and survivin, which inhibit the intrinsic apoptosis pathway and prevent CSC death

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Sci Rep 11:3518 Qi Y, Hu M, Qiu Y et al (2023) Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET

However, the damages were of limited extent and the plants were capable to regenerate damaged tissues and fully recovered to initial state

A problem of persistence: still more questions than answers