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However, in glutathione synthetase deficiency, because the activity of gamma-glutamyl-cysteine synthetase is regulated via feedback inhibition by glutathione, gamma-glutamyl-cysteine and then L-5-oxoproline are overproduced, resulting in the metabolic acidosis and urinary excretion of this compound at levels several hundred-fold above normal (71

Nobuhiro Mori , Keisuke Oda, Hideki Takakura, Yusuke Tanaka, Tomoharu Yokooji, Teruo Murakami, Comparison of Berberine Bioavailability between Oral and Rectal Administrations in Rats, Vol

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[] Lycopene has been recognized as a compound with potent anti-cancer properties, characterized by its widespread availability, relatively low cost, and minimal apparent side effects

Challenges and future directions in deciphering subcellular GSH dynamics are discussed, advocating for innovative methodologies to advance our comprehension and facilitate the development of precise therapeutic interventions based on GSH modulation

Additionally, GA effectively regulated the proliferation and migration of VSMCs by modulating key cell cycle signals and pathways (Chang et al., 2012a